Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697910 | 0.79 | — | — | |
| SCHEMBL21426001 | 0.77 | — | — | |
| SCHEMBL456596 | 0.77 | — | — | |
| SCHEMBL5943069 | 0.77 | — | — | |
| SCHEMBL1819311 | 0.77 | — | — | |
| SCHEMBL7704845 | 0.77 | — | — | |
| SCHEMBL15901770 | 0.76 | MAOA (0.38) | HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL12061582 | 0.76 | MAOA (0.38) | HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL8907193 | 0.75 | CARM1 (0.37) | HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL7708069 | 0.75 | CARM1 (0.37) | HTR2AHTR2CHTR2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280873-A1 | Piperidines, medicines containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-09-07 | — | — | EP | disclosed |