SCHEMBL10696750

SCHEMBL10696750

O=C(O)c1cc(C2CCCCC2)c(O)c(C2CCCCC2)c1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47
MAPT P10636 1/20 0.47
KMT2A Q03164 1/20 0.47
ACMSD Q8TDX5 2/20 0.45
HSP90AA1 P07900 1/20 0.37
CAMKK2 Q96RR4 5/20 0.36
KMO O15229 2/20 0.36
HSD17B10 Q99714 1/20 0.34
CAMKK1 Q8N5S9 3/20 0.34
PTGDR2 Q9Y5Y4 5/20 0.33
PTGDR Q13258 3/20 0.33
DHODH Q02127 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
KDM5A P29375 1/20 0.33
KDM5B Q9UGL1 1/20 0.33
PTGER2 P43116 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14989246 0.87 ACMSD (0.44) KDM4EMEN1MAPTKMT2AACMSD
SCHEMBL9823221 0.87 ACMSD (0.44) KDM4EMEN1MAPTKMT2AACMSD
SCHEMBL14989275 0.84 ACMSD (0.44) KDM4EMEN1MAPTKMT2AACMSD
SCHEMBL14989272 0.83 ACMSD (0.49) KDM4EMEN1MAPTKMT2AACMSD
SCHEMBL11773551 0.80 KDM4E (0.51) KDM4EMEN1MAPTKMT2AACMSD
SCHEMBL14989248 0.80 ACMSD (0.46) KDM4EMEN1MAPTKMT2AACMSD
SCHEMBL11756192 0.80 KDM4E (0.50) KDM4EMEN1MAPTKMT2AACMSD
SCHEMBL11335917 0.79 KDM4E (0.44) KDM4EMEN1MAPTKMT2AACMSD
SCHEMBL11409144 0.78 ACMSD (0.44) KDM4EKMT2AACMSDCAMKK2KMO
SCHEMBL167431 0.78 ACMSD (0.44) KDM4EKMT2AACMSDCAMKK2KMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110234515-B Recording material and recording sheet 日本曹达株式会社 2022-02-11 CN disclosed
CN-110709255-B Recording material and compound 日本曹达株式会社 2021-08-06 CN disclosed
CN-109641472-B Recording material and recording sheet 日本曹达株式会社 2021-07-27 CN disclosed
CN-110709255-A Recording material and compound 日本曹达株式会社 2020-01-17 CN disclosed
US-4727162-A COLOR FORMERS FOR HEAT OR PRESSURE RECORDING MATERIAL SHIN NISSO KAKO CO., LTD. (JP) 1988-02-23 US disclosed
US-4695640-A COLOR FORMER FOR RECORDING MATERIALS SHIN NISSO KAKO CO., LTD. (JP) 1987-09-22 US disclosed