Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.56 |
| ▸ | KCNA5 | P22460 | 6/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL10698242 | 0.93 | KCNA5 (0.60) | KCNA5HPGDALDH1A1MAPT | |
| SCHEMBL7400087 | 0.84 | LTA4H (0.65) | HRH3KCNA5HPGDALDH1A1 | |
| SCHEMBL19025236 | 0.84 | LTA4H (0.65) | HRH3KCNA5PSMB1PSMB5 | |
| SCHEMBL8114904 | 0.83 | LTA4H (0.61) | HRH3KCNA5ALDH1A1 | |
| SCHEMBL6945688 | 0.83 | LTA4H (0.61) | HRH3KCNA5ALDH1A1 | |
| SCHEMBL8337754 | 0.83 | HRH3 (0.70) | HRH3MAPK14PSMB1PSMB5ALDH1A1 | |
| SCHEMBL15834053 | 0.83 | HRH3 (0.66) | HRH3MAPK14PSMB1PSMB5 | |
| Hydrochloric Acid SCHEMBL8972891 | 0.81 | HRH3 (0.68) | HRH3MAPK14PSMB1PSMB5ALDH1A1 | |
| SCHEMBL82435 | 0.81 | HRH3 (0.73) | HRH3MAPK14PSMB1PSMB5 | |
| SCHEMBL10191921 | 0.81 | LTA4H (0.65) | HRH3KCNA5HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252876-A1 | Hydrogenated 1-phenoxyalkylpyridine-3-carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | disclosed |