Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.44 |
| ▸ | HTR2A | P28223 | 6/20 | 0.44 |
| ▸ | HTR2B | P41595 | 6/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18995114 | 0.81 | HTR2C (0.49) | HTR2CHTR2AHTR2BADRB1HTR1A | |
| SCHEMBL19827961 | 0.79 | HTR2C (0.40) | HTR2CHTR2AHTR2BADRB1HTR1A | |
| SCHEMBL19827955 | 0.79 | HTR2C (0.40) | HTR2CHTR2AHTR2BADRB1HTR1A | |
| SCHEMBL19829908 | 0.79 | HTR2C (0.40) | HTR2CHTR2AHTR2BADRB1HTR1A | |
| SCHEMBL19829910 | 0.79 | HTR2C (0.40) | HTR2CHTR2AHTR2BADRB1HTR1A | |
| SCHEMBL30743773 | 0.78 | SLC6A2 (0.37) | HTR2CHTR2AHTR2BSLC6A2SLC6A4 | |
| SCHEMBL15896884 | 0.78 | SLC6A2 (0.37) | HTR2CHTR2AHTR2BSLC6A2SLC6A4 | |
| SCHEMBL13616555 | 0.78 | SLC6A2 (0.37) | HTR2CHTR2AHTR2BSLC6A2SLC6A4 | |
| SCHEMBL5097822 | 0.77 | MAP3K14 (0.42) | HTR2CHTR2AHTR2BADRB1HTR1A | |
| SCHEMBL31394732 | 0.77 | ADRA2A (0.40) | HTR2CHTR2AHTR2BADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200296966-A1 | VOLATILE APPLICATIONS AGAINST PATHOGENS | AGROFRESH INC (US) | 2020-09-24 | — | — | US | disclosed |
| EP-0257378-A1 | Pyrimidine derivatives, their preparation and medicaments containing these derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1988-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200296966-A1 | VOLATILE APPLICATIONS AGAINST PATHOGENS | OXA1L, VAPB, TIAL1 | HTR2C 4476/4885HTR2A 4571/4885HTR2B 1860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.