SCHEMBL10696894

SCHEMBL10696894

CCCCCCCCCCCCOOc1cccc(C)c1C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 3/20 0.49
PPARG P37231 2/20 0.47
BID P55957 3/20 0.46
MCL1 Q07820 3/20 0.46
BCL2L1 Q07817 2/20 0.46
BAK1 Q16611 2/20 0.46
KAT8 Q9H7Z6 2/20 0.46
EP300 Q09472 1/20 0.46
KAT2A Q92830 1/20 0.46
KAT2B Q92831 1/20 0.46
KAT5 Q92993 1/20 0.46
SAE1 Q9UBE0 1/20 0.46
PTPN11 Q06124 2/20 0.44
PTPN1 P18031 1/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
NR1I2 O75469 1/20 0.43
LMNA P02545 1/20 0.43
CHRM2 P08172 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9502979 0.87 MEN1 (0.52) PPARAPPARGPTPN11PTPN1MEN1
SCHEMBL9504277 0.87 MEN1 (0.52) PPARAPPARGPTPN11PTPN1MEN1
SCHEMBL10339837 0.81 TP53 (0.50) PPARAPPARGPTPN1TDP1TP53
SCHEMBL8820845 0.80 MEN1 (0.48) PPARAPPARGBIDMCL1BCL2L1
SCHEMBL458733 0.78 PTPN11 (0.56) PTPN11PTPN1MEN1KMT2ANR1I2
SCHEMBL10696272 0.78 PTPN11 (0.56) PTPN11PTPN1MEN1KMT2ANR1I2
SCHEMBL9845259 0.78 PTPN11 (0.56) PTPN11PTPN1MEN1KMT2ANR1I2
SCHEMBL9845254 0.78 PTPN11 (0.56) PTPN11PTPN1MEN1KMT2ANR1I2
SCHEMBL10697083 0.78 PTPN11 (0.56) PTPN11PTPN1MEN1KMT2ANR1I2
SCHEMBL6256221 0.78 PTPN11 (0.56) PTPN11PTPN1MEN1KMT2ANR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0275203-A2 Heat-sensitive recording material containing color forming components FUJI PHOTO FILM CO., LTD. (JP) 1988-07-20 EP disclosed