SCHEMBL458733

SCHEMBL458733

CCCCCCCOOc1ccccc1C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 4/20 0.56
KMT2A Q03164 3/20 0.56
MEN1 O00255 2/20 0.56
LMNA P02545 2/20 0.56
CYP3A4 P08684 2/20 0.56
KDM4E B2RXH2 2/20 0.56
RECQL P46063 1/20 0.56
NR1I2 O75469 1/20 0.56
CHRM2 P08172 1/20 0.56
ADRA2A P08913 1/20 0.56
MAPT P10636 1/20 0.56
OPRK1 P41145 1/20 0.56
HTR2B P41595 1/20 0.56
SLC6A3 Q01959 1/20 0.56
HDAC6 Q9UBN7 1/20 0.56
ALDH1A1 P00352 5/20 0.54
TSHR P16473 2/20 0.54
TP53 P04637 1/20 0.51
MAPK1 P28482 1/20 0.51
PTPN1 P18031 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10697083 1.00 PTPN11 (0.56) PTPN11KMT2AMEN1LMNACYP3A4
SCHEMBL10697930 1.00 PTPN11 (0.56) PTPN11KMT2AMEN1LMNACYP3A4
SCHEMBL10695467 1.00 PTPN11 (0.56) PTPN11KMT2AMEN1LMNACYP3A4
SCHEMBL9845259 1.00 PTPN11 (0.56) PTPN11KMT2AMEN1LMNACYP3A4
SCHEMBL9845254 1.00 PTPN11 (0.56) PTPN11KMT2AMEN1LMNACYP3A4
SCHEMBL10696272 1.00 PTPN11 (0.56) PTPN11KMT2AMEN1LMNACYP3A4
SCHEMBL6256221 1.00 PTPN11 (0.56) PTPN11KMT2AMEN1LMNACYP3A4
SCHEMBL8369187 0.98 KMT2A (0.57) PTPN11KMT2AMEN1LMNACYP3A4
SCHEMBL6693055 0.94 KDM4E (0.59) PTPN11KMT2AMEN1LMNACYP3A4
Vinyl Chloride SCHEMBL28276528 0.90 KMT2A (0.50) PTPN11KMT2AMEN1LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024020463-A2 COSMETIC COMPOSITION COTY INC. (US) 2024-01-25 WO disclosed
EP-4271356-A1 COMPOSITION FOR KERATIN FIBERS L'OREAL (FR) 2023-11-08 EP disclosed
WO-2023118075-A1 ANTI-IMPERFECTION AQUEOUS MAKEUP REMOVING COMPOSITION L'OREAL (FR) 2023-06-29 WO disclosed
WO-2022118980-A1 COMPOSITION FOR KERATIN FIBERS L'OREAL (FR) 2022-06-09 WO disclosed
WO-2022118978-A1 COMPOSITION FOR KERATIN FIBERS L'OREAL (FR) 2022-06-09 WO disclosed
WO-2022118982-A1 PROCESS FOR TREATING KERATIN FIBERS L'OREAL (FR) 2022-06-09 WO disclosed
WO-2018154086-A1 COLOURED KERATOLYTIC NAIL LACQUER OYSTERSHELL NV (BE) 2018-08-30 WO disclosed
EP-2890359-A1 DICKKOPF-1 EXPRESSION MODULATING COMPOSITIONS AND USES THEREOF Avon Products, Inc. (US) 2015-07-08 EP disclosed
EP-2790666-A2 MAESA JAPONICA EXTRACTS AND METHODS OF USE Avon Products, Inc. (US) 2014-10-22 EP disclosed
WO-2014163717-A1 HOYA CARNOSA EXTRACTS AND METHODS OF USE AVON PRODUCTS, INC. (US) 2014-10-09 WO disclosed
EP-1763341-A2 COMPOSITIONS AND METHODS FOR TREATING PATHOLOGICAL INFECTIONS Warner-Lambert Company LLC (US) 2007-03-21 EP disclosed
WO-2006120646-A1 TOPICAL USE OF TEPRENONE SEDERMA (FR) 2006-11-16 WO disclosed
WO-2006068778-A2 THE USE OF PLANT EXTRACTS TO PREVENT AND/OR REDUCE THE SIGNS OF SUBJECTIVE DISCOMFORT AND/OR IRRITATION IN THE TOPICAL APPLICATION OF COSMETIC PRODUCTS AVON PRODUCTS, INC. (US) 2006-06-29 WO disclosed
WO-2006068786-A2 COMPOSITIONS AND METHODS OF THEIR USE FOR IMPROVING THE CONDITION AND APPEARANCE OF SKIN AVON PRODUCTS, INC. (US) 2006-06-29 WO disclosed
WO-2006068777-A2 USE OF NATURAL PLANT EXTRACTS IN COSMETICS COMPOSITIONS AVON PRODUCTS, INC. (US) 2006-06-29 WO disclosed
WO-2006068779-A2 COMPOSITIONS AND METHODS OF THEIR USE FOR IMPROVING THE CONDITION AND APPEARANCE OF SKIN AVON PRODUCTS, INC. (US) 2006-06-29 WO disclosed
WO-2006068776-A1 USE OF ALISMA ORIENTALE IN COSMETICS AND COMPOSITIONS THEREOF AVON PRODUCTS, INC. (US) 2006-06-29 WO disclosed
WO-2006003492-A2 COMPOSITIONS AND METHODS FOR TREATING PATHOLOGICAL INFECTIONS WARNER-LAMBERT COMPANY LLC (US) 2006-01-12 WO disclosed
EP-1549331-A2 USE OF PURSLANE TO TREAT FACIAL WRINKLES Avon Products, Inc. (US) 2005-07-06 EP disclosed
WO-2004060289-A2 USE OF PURSLANE TO TREAT FACIAL WRINKLES AVON PRODUCTS, INC. (US) 2004-07-22 WO disclosed