SCHEMBL10696974

SCHEMBL10696974

Clc1cccc(SSc2ccccc2)c1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.50
HPGD P15428 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
MGLL Q99685 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
HTR1A P08908 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
HTR3A P46098 1/20 0.37
TSHR P16473 3/20 0.37
LDHA P00338 1/20 0.36
LMNA P02545 2/20 0.36
FBP1 P09467 1/20 0.36
PNMT P11086 1/20 0.34
NPSR1 Q6W5P4 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL943125 0.87 TSHR (0.46) MAPTMEN1KMT2ACYP1A2CYP3A4
SCHEMBL8855670 0.85 HPGD (0.57) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL1158036 0.81 CYP1A2 (0.45) MAPTHPGDMEN1KMT2ACYP1A2
SCHEMBL144374 0.73 HPGD (0.48) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL8432424 0.72 FBP1 (0.44) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL31438320 0.72 CYP1A2 (0.51) MAPTMEN1KMT2ACYP1A2CYP3A4
SCHEMBL9812315 0.72 CYP1A2 (0.51) MAPTMEN1KMT2ACYP1A2CYP3A4
SCHEMBL31464849 0.71 FBP1 (0.55) MAPTMEN1KMT2ACYP1A2TSHR
SCHEMBL225608 0.71 FBP1 (0.55) MAPTMEN1KMT2ACYP1A2TSHR
SCHEMBL7759264 0.71 HPGD (1.00) MAPTHPGDSMN1; SMN2MGLLHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108565397-B Surface oxidation composite protective layer structure of lithium metal electrode and preparation method 四川华昆能源有限责任公司 2020-10-09 CN disclosed
EP-0281036-A2 A process for preparing a polyarylene thioether IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1988-09-07 EP disclosed
US-3971820-A TETRAMIZATION OF HALOGEN CYANIDE, BASIC CATALYST NIPPON SODA COMPANY LIMITED (JA) 1976-07-27 US disclosed