Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL1050270 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TSHRHMGCRCHRM1TBXA2R | |
| Trimethylammonium SCHEMBL3298074 | 0.77 | — | — | |
| SCHEMBL2428258 | 0.77 | — | — | |
| Water SCHEMBL2817950 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL5157333 | 0.73 | — | — | |
| Fluoride SCHEMBL4617073 | 0.73 | — | — | |
| SCHEMBL27448165 | 0.69 | TSHR (0.44) | ALDH1A1TSHRHMGCRCHRM1TBXA2R | |
| SCHEMBL10381795 | 0.69 | ALDH1A1 (0.30) | ALDH1A1TSHR | |
| Bicarbonate SCHEMBL9818559 | 0.69 | CA4 (0.46) | CA1 | |
| Bicarbonate SCHEMBL3369000 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269949-A2 | Process for producing a high purity quaternary ammonium hydroxide | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1988-06-08 | — | — | EP | claimed |