Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 3/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11666641 | 0.85 | MAPT (0.34) | MAPTHCAR2HCAR3TYMPTLR8 | |
| SCHEMBL4981698 | 0.80 | GAA (0.30) | GAA | |
| SCHEMBL2733972 | 0.78 | TLR8 (0.40) | MAPTTYMPTLR8TLR7GAA | |
| SCHEMBL17500332 | 0.77 | MAPT (0.41) | MAPTHCAR2HCAR3TYMPTLR8 | |
| SCHEMBL8636988 | 0.72 | GAA (0.33) | MAPTTYMPTLR8TLR7GAA | |
| SCHEMBL6683717 | 0.71 | MAPT (0.47) | MAPTTYMPTLR8TLR7GAA | |
| SCHEMBL8639882 | 0.69 | GAA (0.36) | MAPTGAATSHRLMNAMAPK1 | |
| SCHEMBL3643513 | 0.69 | BRD4 (0.36) | GAA | |
| SCHEMBL3664202 | 0.67 | GAA (0.42) | MAPTHCAR2HCAR3GAATSHR | |
| SCHEMBL13516628 | 0.66 | MAPK1 (0.37) | MAPTGAATSHRLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257479-A1 | Substituted 1-aryl-3-tert.-butyl pyrazoles | BAYER AG (DE) | 1988-03-02 | — | — | EP | disclosed |