Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TYMP | P19971 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13516628 | 0.88 | MAPK1 (0.37) | MAPTMAPK1LMNAGAASMN1; SMN2 | |
| SCHEMBL17500332 | 0.82 | MAPT (0.41) | TLR8TLR7MAPTTYMPMAPK1 | |
| SCHEMBL21145592 | 0.79 | MAPK1 (0.55) | MAPTMAPK1LMNAGAASMN1; SMN2 | |
| SCHEMBL10697030 | 0.78 | MAPT (0.35) | TLR8TLR7MAPTTYMPMAPK1 | |
| SCHEMBL9049048 | 0.78 | KDM4E (0.36) | MAPK1LMNASMN1; SMN2TSHRMEN1 | |
| SCHEMBL11438926 | 0.78 | HSD17B10 (0.54) | MAPTMAPK1LMNAGAASMN1; SMN2 | |
| SCHEMBL10180518 | 0.78 | HSD17B10 (0.54) | MAPTMAPK1LMNAGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6559450 | 0.78 | KDM4E (0.40) | MAPTMAPK1LMNASMN1; SMN2MEN1 | |
| SCHEMBL11440996 | 0.78 | HSD17B10 (0.54) | MAPTMAPK1LMNAGAASMN1; SMN2 | |
| SCHEMBL11437970 | 0.78 | HSD17B10 (0.54) | MAPTMAPK1LMNAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2629776-A2 | COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILISATION | Cerenis Therapeutics Holding SA (FR) | 2013-08-28 | — | — | EP | disclosed |
| WO-2012054535-A2 | COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILISATION | CERENIS THERAPEUTICS SA (FR) | 2012-04-26 | — | — | WO | disclosed |