SCHEMBL10697260

SCHEMBL10697260

O=C(c1ccccc1)c1ccccc1Oc1ccc(O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 1/20 0.53
LIG1 P18858 1/20 0.51
LMNA P02545 3/20 0.50
MAPK1 P28482 2/20 0.50
ELANE P08246 2/20 0.50
ALDH1A1 P00352 1/20 0.50
CYP1A2 P05177 1/20 0.50
PGR P06401 1/20 0.50
CYP2D6 P10635 1/20 0.50
HPGD P15428 1/20 0.50
SLC6A2 P23975 1/20 0.50
PDE4A P27815 1/20 0.50
CYP2C19 P33261 1/20 0.50
HRH1 P35367 1/20 0.50
HTT P42858 1/20 0.50
SLC6A3 Q01959 1/20 0.50
PDE4D Q08499 1/20 0.50
LTA4H P09960 1/20 0.50
NR1H2 P55055 1/20 0.50
BAX Q07812 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10534226 0.95 LIG1 (0.58) CTNNB1LIG1LMNAMAPK1ALDH1A1
SCHEMBL10536985 0.90 LMNA (0.54) CTNNB1LIG1LMNAMAPK1ALDH1A1
SCHEMBL9419499 0.90 SRD5A2 (0.58) CTNNB1LMNAMAPK1ELANEALDH1A1
SCHEMBL4631035 0.90 CTNNB1 (0.65) CTNNB1LMNAMAPK1ELANEALDH1A1
SCHEMBL8648432 0.90 CTNNB1 (0.55) CTNNB1LIG1LMNAELANEALDH1A1
SCHEMBL5846836 0.89 MAPK1 (0.48) CTNNB1LIG1LMNAMAPK1ELANE
SCHEMBL28378390 0.88 LMNA (0.49) CTNNB1LIG1LMNAMAPK1ELANE
Benzophenone SCHEMBL28468666 0.88 CTNNB1 (0.62) CTNNB1LMNAMAPK1ELANEALDH1A1
SCHEMBL8648435 0.88 LIG1 (0.46) CTNNB1LIG1LMNAMAPK1ELANE
SCHEMBL10586309 0.87 CDC25B (0.54) CTNNB1LMNAMAPK1ELANEMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105593267-A Polymeric material VICTREX MFG LTD 2016-05-18 CN disclosed
EP-0275037-A2 Aryl ether ketones BASF Aktiengesellschaft (DE) 1988-07-20 EP disclosed
WO-1985004176-A1 A PROCESS FOR PREPARAING VINYL ESTER RESINS CONTAINING TRIAZINE OR BOTH TRIAZINE AND OXAZOLINE GROUPS THE DOW CHEMICAL COMPANY (US) 1985-09-26 WO disclosed