Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 5/20 | 0.69 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.69 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.57 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.56 |
| ▸ | DHFR | P00374 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19160930 | 1.00 | LTB4R (0.69) | LTB4RLTB4R2CYSLTR2CYSLTR1NPSR1 | |
| SCHEMBL11668948 | 1.00 | LTB4R (0.69) | LTB4RLTB4R2CYSLTR2CYSLTR1NPSR1 | |
| SCHEMBL8081137 | 1.00 | LTB4R (0.69) | LTB4RLTB4R2CYSLTR2CYSLTR1NPSR1 | |
| SCHEMBL8084778 | 1.00 | LTB4R (0.69) | LTB4RLTB4R2CYSLTR2CYSLTR1NPSR1 | |
| SCHEMBL8081157 | 0.98 | LTB4R (0.67) | LTB4RLTB4R2CYSLTR2CYSLTR1NPSR1 | |
| SCHEMBL8072582 | 0.94 | LTB4R (0.64) | LTB4RLTB4R2CYSLTR2CYSLTR1NPSR1 | |
| SCHEMBL25168636 | 0.92 | LTB4R (0.77) | LTB4RLTB4R2CYSLTR2CYSLTR1NPSR1 | |
| SCHEMBL8084798 | 0.89 | LTB4R (0.62) | LTB4RLTB4R2NPSR1DHFRMEN1 | |
| SCHEMBL19160785 | 0.88 | LTB4R (0.55) | LTB4RLTB4R2MEN1NR1I2LMNA | |
| SCHEMBL17345291 | 0.88 | LTB4R (0.55) | LTB4RLTB4R2MEN1NR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120208709-A1 | GENETIC SUSCEPTIBILITY VARIANTS ASSOCIATED WITH CARDIOVASCULAR DISEASE | DECODE GENETICS EHF. (IS) | 2012-08-16 | — | — | US | disclosed |
| EP-0276064-A1 | Anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1988-07-27 | — | — | EP | disclosed |