Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22634102 | 0.84 | AKR1C3 (0.55) | MCL1AKR1C3ALDH1A1TSHRAKR1C1 | |
| SCHEMBL689448 | 0.84 | AKR1C3 (0.55) | MCL1AKR1C3ALDH1A1TSHRAKR1C1 | |
| SCHEMBL194553 | 0.82 | MCL1 (0.55) | MCL1AKR1C3ALDH1A1TSHRAKR1C1 | |
| SCHEMBL16159989 | 0.82 | AKR1C3 (0.53) | MCL1AKR1C3ALDH1A1TSHRAKR1C1 | |
| SCHEMBL11448260 | 0.81 | MCL1 (0.41) | MCL1AKR1C3ALDH1A1TSHRFBP1 | |
| SCHEMBL11799882 | 0.79 | AKR1C1 (0.48) | AKR1C3ALDH1A1TSHRAKR1C1MEN1 | |
| SCHEMBL11799886 | 0.79 | AKR1C1 (0.48) | AKR1C3ALDH1A1TSHRAKR1C1MEN1 | |
| SCHEMBL1898750 | 0.78 | MCL1 (0.46) | MCL1AKR1C3ALDH1A1TSHRAKR1C1 | |
| SCHEMBL24370519 | 0.78 | MEN1 (0.46) | AKR1C3RECQLMEN1KMT2A | |
| SCHEMBL4998842 | 0.78 | MEN1 (0.46) | AKR1C3RECQLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274546-A1 | New oxazolinone compounds useful as intermediates for the preparation of insecticidal and acaracidal cinnamide compounds | AMERICAN CYANAMID COMPANY (US) | 1988-07-20 | — | — | EP | claimed |