SCHEMBL194553

SCHEMBL194553

NC(=O)C(=Cc1ccccc1)C(O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.55
AKR1C3 P42330 1/20 0.44
AKR1C1 Q04828 1/20 0.42
FBP1 P09467 1/20 0.40
ALDH1A1 P00352 3/20 0.40
MAPT P10636 3/20 0.40
LMNA P02545 2/20 0.40
KDM4E B2RXH2 2/20 0.40
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.39
CYP2C9 P11712 2/20 0.39
CYP3A4 P08684 1/20 0.39
RECQL P46063 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
HDAC3 O15379 1/20 0.38
TNKS O95271 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HCAR2 Q8TDS4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1563519 0.83 AKR1C3 (0.52) MCL1AKR1C3AKR1C1FBP1ALDH1A1
SCHEMBL10697322 0.82 MCL1 (0.53) MCL1AKR1C3AKR1C1FBP1ALDH1A1
SCHEMBL10410499 0.80 MCL1 (0.47) MCL1AKR1C3AKR1C1FBP1ALDH1A1
SCHEMBL16179542 0.74 MCL1 (0.57) MCL1AKR1C3AKR1C1FBP1ALDH1A1
SCHEMBL1628729 0.74 MCL1 (0.57) MCL1AKR1C3AKR1C1FBP1ALDH1A1
SCHEMBL1096966 0.74 MCL1 (0.57) MCL1AKR1C3AKR1C1FBP1ALDH1A1
SCHEMBL20049735 0.74 MCL1 (0.57) MCL1AKR1C3AKR1C1FBP1ALDH1A1
SCHEMBL17397066 0.74 MCL1 (0.57) MCL1AKR1C3AKR1C1FBP1ALDH1A1
SCHEMBL1259438 0.74 MCL1 (0.57) MCL1AKR1C3AKR1C1FBP1ALDH1A1
SCHEMBL11594648 0.74 MCL1 (0.57) MCL1AKR1C3AKR1C1FBP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9365515-B2 Oxime ester photoinitiators BASF SE (DE) 2016-06-14 US disclosed
US-20140334027-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2014-11-13 US disclosed
US-8524425-B2 Oxime ester photoinitiators BASF SE (DE) 2013-09-03 US disclosed
US-8349548-B2 Oxime ester photoinitiators BASF SE (DE) 2013-01-08 US disclosed
US-8148358-B2 Blue colour filters with enhanced contrast BASF SE (DE) 2012-04-03 US disclosed
EP-2285836-B1 PHOTOINITIATOR MIXTURES BASF SE (DE) 2012-01-18 EP disclosed
EP-2402315-A1 Oxime ester photoinitiators BASF SE (DE) 2012-01-04 EP disclosed
EP-1410109-B1 PHOTOSENSITIVE RESIN COMPOSITION BASF SE (DE) 2011-10-26 EP disclosed
US-20110218266-A1 PHOTOINITIATOR MIXTURES BASF SE (DE) 2011-09-08 US disclosed
US-20110170209-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2011-07-14 US disclosed
US-20070259278-A1 Photosensitive resin composition IGM GROUP B.V. (NL) 2007-11-08 US disclosed
US-20070249748-A1 Photosensitive resin composition IGM GROUP B.V. (NL) 2007-10-25 US disclosed
US-7247659-B2 Photosensitive resin composition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-07-24 US disclosed
US-20060241259-A1 Oxime ester photoinitiators with heteroaromatic groups CIBA CORPORATION 2006-10-26 US disclosed
US-20040192804-A1 Photosensitive resin composition IGM GROUP B.V. (NL) 2004-09-30 US disclosed
EP-0815280-B1 THERMAL DEPOSITION METHOD FOR DEPOSITING THIN CERAMIC LAYERS AND AN ASSOCIATED DEVICE HOECHST AG (DE) 1999-07-07 EP disclosed
EP-0815280-A1 THERMAL DEPOSITION METHOD FOR DEPOSITING THIN CERAMIC LAYERS AND AN ASSOCIATED DEVICE HOECHST AKTIENGESELLSCHAFT (DE) 1998-01-07 EP disclosed
EP-0649063-B1 Matted radiation-sensitive recording material AGFA GEVAERT AG (DE) 1997-01-29 EP disclosed
WO-1996029443-A1 THERMAL DEPOSITION METHOD FOR DEPOSITING THIN CERAMIC LAYERS AND AN ASSOCIATED DEVICE HOECHST AKTIENGESELLSCHAFT (DE) 1996-09-26 WO disclosed
EP-0649063-A1 Matted radiation-sensitive recording material HOECHST AKTIENGESELLSCHAFT (DE) 1995-04-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140334027-A1 OXIME ESTER PHOTOINITIATORS CBR3, OR10J3, CHRM1 MCL1 4173/4885AKR1C3 197/4885AKR1C1 322/4885
US-20110170209-A1 OXIME ESTER PHOTOINITIATORS RAD51, CBR3, CBR1 MCL1 1558/4885AKR1C3 89/4885AKR1C1 97/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.