Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695164 | 0.90 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9636148 | 0.89 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL10697924 | 0.89 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9473967 | 0.89 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL10694326 | 0.87 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL10698149 | 0.87 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL5187061 | 0.83 | KCNH2 (0.49) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL10697767 | 0.83 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL10646491 | 0.82 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL8803590 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276700-A1 | 8-Cyano-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids, process for their preparation, and antibacterial agents containing them | BAYER AG (DE) | 1988-08-03 | — | — | EP | disclosed |