Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 4/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697971 | 0.99 | TSHR (0.40) | TSHRHPGDPLA2G2CHCAR2ALDH1A1 | |
| SCHEMBL7691175 | 0.78 | THRB (0.36) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL7690556 | 0.78 | TSHR (0.39) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL7683840 | 0.77 | THRB (0.41) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL10699859 | 0.76 | PLA2G2C (0.40) | TSHRHPGDPLA2G2CHCAR2 | |
| SCHEMBL10482045 | 0.75 | THRB (0.39) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL7685240 | 0.74 | TSHR (0.36) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL11415578 | 0.73 | LPAR1 (0.42) | PLA2G2CHCAR2CYP3A4USP2 | |
| SCHEMBL11751232 | 0.73 | MEN1 (0.45) | TSHRHPGDPLA2G2CALDH1A1TP53 | |
| SCHEMBL10699703 | 0.73 | TSHR (0.51) | TSHRPLA2G2CHCAR2ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289933-A2 | Graft polymerization precurser and method manufacturing the same | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1988-11-09 | — | — | EP | disclosed |
| EP-0277608-A2 | Graft polymerization preformer and method of manufacturing the same | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1988-08-10 | — | — | EP | disclosed |