Coumaric Acid

Coumaric Acid

SCHEMBL10697515

CCCC.O=C(O)C=Cc1ccc(O)cc1

nearest known ligand 0.81

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.81
CA12 O43570 4/20 0.81
CA1 P00915 4/20 0.81
CA2 P00918 4/20 0.81
CA7 P43166 4/20 0.81
CA9 Q16790 4/20 0.81
CA14 Q9ULX7 4/20 0.81
ESR2 Q92731 3/20 0.81
TYR P14679 3/20 0.81
AKR1B10 O60218 3/20 0.81
AKR1B1 P15121 3/20 0.81
HCAR2 Q8TDS4 2/20 0.81
PKM P14618 2/20 0.81
CA3 P07451 2/20 0.81
CA4 P22748 2/20 0.81
CA6 P23280 2/20 0.81
DPP4 P27487 2/20 0.81
CA5A P35218 2/20 0.81
CA5B Q9Y2D0 2/20 0.81
PGR P06401 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Coumaric Acid SCHEMBL27971070 0.98 ESR1 (0.78) ESR1CA12CA1CA2CA7
Coumaric Acid SCHEMBL28854325 0.92 ESR1 (0.81) ESR1CA12CA1CA2CA7
Coumaric Acid SCHEMBL4740382 0.90 CA12 (0.91) ESR1CA12CA1CA2CA7
Coumaric Acid SCHEMBL43601 0.90 ESR1 (1.00) ESR1CA12CA1CA2CA7
Coumaric Acid SCHEMBL20702657 0.90 ESR1 (1.00) ESR1CA12CA1CA2CA7
Coumaric Acid SCHEMBL39106 0.90 ESR1 (1.00) ESR1CA12CA1CA2CA7
Coumaric Acid SCHEMBL6333102 0.90 ESR1 (1.00) ESR1CA12CA1CA2CA7
Coumaric Acid SCHEMBL6333097 0.90 ESR1 (1.00) ESR1CA12CA1CA2CA7
Coumaric Acid SCHEMBL434720 0.90 ESR1 (1.00) ESR1CA12CA1CA2CA7
Coumaric Acid SCHEMBL17443295 0.88 CA12 (0.88) ESR1CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102883753-A Drug-releasing coatings for medical devices LUTONIX INC 2013-01-16 CN claimed
CN-87107947-A hot fumigator 1988-08-31 CN claimed
CN-108424683-A Solventbased inkjet ink composition 内蒙古显鸿科技股份有限公司 2018-08-21 CN disclosed
CN-108291121-A Anisotropic conductive film and connection structure using the same 三星SDI株式会社 2018-07-17 CN disclosed
CN-104857573-A Drug releasing coating for medical device LUTONIX INC 2015-08-26 CN disclosed
CN-102883753-B Drug-releasing coatings for medical devices LUTONIX INC 2015-04-15 CN disclosed
CN-102883753-A Drug-releasing coatings for medical devices LUTONIX INC 2013-01-16 CN disclosed
CN-101875876-A Lubricating oil composition INFINEUM INT LTD 2010-11-03 CN disclosed
EP-0266994-A2 Process for the grafting of monomers onto polymers Du Pont Canada Inc. (CA) 1988-05-11 EP disclosed