Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.85 |
| ▸ | CA1 | P00915 | 4/20 | 0.85 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 4/20 | 0.47 |
| ▸ | MMP3 | P08254 | 4/20 | 0.47 |
| ▸ | MMP2 | P08253 | 3/20 | 0.47 |
| ▸ | MMP7 | P09237 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20915578 | 1.00 | CA2 (0.85) | CA2CA1HDAC8HDAC6HDAC7 | |
| SCHEMBL20915289 | 1.00 | CA2 (0.85) | CA2CA1HDAC8HDAC6HDAC7 | |
| SCHEMBL21389651 | 1.00 | CA2 (0.85) | CA2CA1HDAC8HDAC6HDAC7 | |
| SCHEMBL20936513 | 1.00 | CA2 (0.85) | CA2CA1HDAC8HDAC6HDAC7 | |
| SCHEMBL20915253 | 1.00 | CA2 (0.85) | CA2CA1HDAC8HDAC6HDAC7 | |
| SCHEMBL20915508 | 1.00 | CA2 (0.85) | CA2CA1HDAC8HDAC6HDAC7 | |
| SCHEMBL20936460 | 1.00 | CA2 (0.85) | CA2CA1HDAC8HDAC6HDAC7 | |
| SCHEMBL3667269 | 0.98 | CA2 (0.88) | CA2CA1HDAC8HDAC6HDAC7 | |
| SCHEMBL8054453 | 0.92 | CA2 (1.00) | CA2CA1HDAC8HDAC6HDAC7 | |
| SCHEMBL24932772 | 0.92 | CA2 (0.70) | CA2CA1HDAC8HDAC6HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273274-A2 | Degradation of polyethylene by means of agents generating free radicals | Elf Atochem Deutschland GmbH (DE) | 1988-07-06 | — | — | EP | disclosed |
| US-4374938-A | HYDROXIMIC ACID DERIVATIVE AS FREE RADICAL INITIATOR | AKZONA INCORPORATED (US) | 1983-02-22 | — | — | US | disclosed |
| US-4347342-A | Process for initiating radical reactions employing hydroximic acid derivatives | AKZONA INCORPORATED (US) | 1982-08-31 | — | — | US | disclosed |