Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MERTK | Q12866 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.46 |
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 9/20 | 0.41 |
| ▸ | GSR | P00390 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697897 | 0.83 | MAPT (0.55) | MAPTMERTKHTTFGFR4RPS6KB2 | |
| SCHEMBL1242494 | 0.81 | MAPT (0.59) | MAPTMERTKHTTFGFR4RPS6KB2 | |
| SCHEMBL29636874 | 0.81 | MAPT (0.59) | MAPTMERTKHTTFGFR4RPS6KB2 | |
| SCHEMBL31515714 | 0.81 | MAPT (0.59) | MAPTMERTKHTTFGFR4RPS6KB2 | |
| SCHEMBL8246245 | 0.78 | MAPT (0.59) | MAPTMERTKHTTFGFR4RPS6KB2 | |
| SCHEMBL5091991 | 0.77 | MAPT (0.55) | MAPTMERTKHTTFGFR4RPS6KB2 | |
| SCHEMBL1978817 | 0.77 | MAPT (0.67) | MAPTMERTKHTTFGFR4RPS6KB2 | |
| SCHEMBL21522837 | 0.77 | MAPT (0.55) | MAPTMERTKHTTFGFR4RPS6KB2 | |
| SCHEMBL30154422 | 0.77 | MAPT (0.67) | MAPTMERTKHTTFGFR4RPS6KB2 | |
| SCHEMBL27211667 | 0.77 | MAPT (0.68) | MAPTMERTKHTTFGFR4RPS6KB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |