Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.48 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9194877 | 0.95 | L3MBTL1 (0.66) | L3MBTL1ALDH1A1NPSR1NPC1LMNA | |
| SCHEMBL9193399 | 0.95 | L3MBTL1 (0.66) | L3MBTL1ALDH1A1NPSR1NPC1LMNA | |
| SCHEMBL9195030 | 0.95 | L3MBTL1 (0.66) | L3MBTL1ALDH1A1NPSR1NPC1LMNA | |
| SCHEMBL10700120 | 0.94 | L3MBTL1 (0.72) | L3MBTL1ALDH1A1NPSR1SMN1; SMN2SPHK1 | |
| SCHEMBL10406132 | 0.93 | L3MBTL1 (0.68) | L3MBTL1ALDH1A1NPSR1NPC1LMNA | |
| SCHEMBL9200790 | 0.91 | L3MBTL1 (0.66) | L3MBTL1ALDH1A1NPSR1NPC1LMNA | |
| SCHEMBL9196978 | 0.91 | L3MBTL1 (0.60) | L3MBTL1ALDH1A1NPSR1NPC1LMNA | |
| SCHEMBL10406582 | 0.90 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1NPSR1NPC1LMNA | |
| SCHEMBL10697199 | 0.90 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1NPSR1NPC1LMNA | |
| SCHEMBL9200393 | 0.89 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1NPSR1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0275522-A2 | Optically active 1-acyl-proline esters and their use as doping agents in liquid-crystal compositions | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-27 | — | — | EP | claimed |