Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32688556 | 0.81 | KDM4E (0.37) | KDM4ELMNAEPHX2ALDH1A1 | |
| SCHEMBL10347490 | 0.81 | KDM4E (0.39) | KDM4ELMNAEPHX2ALDH1A1TDP1 | |
| SCHEMBL32689192 | 0.80 | KDM4E (0.36) | KDM4ELMNAEPHX2ALDH1A1 | |
| SCHEMBL32689197 | 0.78 | KDM4E (0.34) | KDM4ELMNAEPHX2ALDH1A1 | |
| SCHEMBL32689092 | 0.77 | KDM4E (0.40) | KDM4ELMNAEPHX2ALDH1A1TDP1 | |
| SCHEMBL1088788 | 0.75 | NPC1 (0.36) | KDM4ELMNAEPHX2ALDH1A1TDP1 | |
| SCHEMBL4608572 | 0.74 | KDM4E (0.38) | KDM4ELMNAEPHX2ALDH1A1TDP1 | |
| SCHEMBL3293689 | 0.73 | KDM4E (0.39) | KDM4ELMNAEPHX2ALDH1A1TDP1 | |
| SCHEMBL12729995 | 0.72 | KDM4E (0.33) | KDM4ELMNAALDH1A1TDP1GAA | |
| SCHEMBL11604002 | 0.72 | KDM4E (0.38) | KDM4ELMNAEPHX2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267537-A2 | Process for the preparation of vinylglyoxal derivatives, vinylglyoxal derivatives and their use | BASF Aktiengesellschaft (DE) | 1988-05-18 | — | — | EP | disclosed |