SCHEMBL10697698

SCHEMBL10697698

Cc1ccc2c(Cl)ccc(N)c2n1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.51
NR4A2 P43354 2/20 0.46
KDM4E B2RXH2 7/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.42
CCR1 P32246 1/20 0.41
RAB9A P51151 1/20 0.41
CCR5 P51681 1/20 0.41
HTT P42858 2/20 0.40
PKM P14618 1/20 0.40
KMT2A Q03164 5/20 0.39
OPRK1 P41145 1/20 0.39
GAA P10253 2/20 0.38
TSHR P16473 1/20 0.36
ADORA1 P30542 2/20 0.36
ADORA2A P29274 1/20 0.36
ALDH1A1 P00352 3/20 0.35
NPC1 O15118 1/20 0.35
USP2 O75604 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11557724 0.85 NR4A2 (0.59) MAPTNR4A2KDM4ETDP1L3MBTL1
SCHEMBL25097371 0.80 MAPT (0.55) MAPTNR4A2KDM4EL3MBTL1CCR1
SCHEMBL1562545 0.80 KMT2A (0.60) MAPTNR4A2KDM4ETDP1L3MBTL1
SCHEMBL20838482 0.78 MAPT (0.49) MAPTNR4A2KDM4ETDP1L3MBTL1
SCHEMBL4738026 0.77 MAPT (0.66) MAPTNR4A2KDM4EL3MBTL1CCR1
SCHEMBL1714753 0.77 MAPT (0.51) MAPTNR4A2KDM4EL3MBTL1CCR1
SCHEMBL17774714 0.77 KMT2A (0.56) MAPTNR4A2KDM4ETDP1CCR1
SCHEMBL25096667 0.77 MAPT (0.51) MAPTNR4A2KDM4EL3MBTL1CCR1
SCHEMBL11901636 0.77 KDM4E (0.44) MAPTNR4A2KDM4ETDP1CCR1
SCHEMBL30217780 0.77 MAPT (0.51) MAPTNR4A2KDM4EL3MBTL1CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0282893-A2 Pesticides based on 1,10-phenanthrolines BAYER AG (DE) 1988-09-21 EP disclosed