Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | BAD | Q92934 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25788072 | 0.87 | ALDH1A1 (0.67) | PTPN11HTTALDH1A1KMT2APTK2B | |
| SCHEMBL3624724 | 0.87 | ALDH1A1 (0.67) | PTPN11HTTALDH1A1KMT2APTK2B | |
| SCHEMBL8722933 | 0.87 | ALDH1A1 (0.67) | PTPN11HTTALDH1A1KMT2APTK2B | |
| SCHEMBL8906750 | 0.87 | ALDH1A1 (0.67) | PTPN11HTTALDH1A1KMT2APTK2B | |
| SCHEMBL10751527 | 0.87 | PTPN11 (0.70) | PTPN11ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL10748772 | 0.87 | PTPN11 (0.70) | PTPN11ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL10752229 | 0.87 | PTPN11 (0.70) | PTPN11ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL10751579 | 0.87 | PTPN11 (0.70) | PTPN11ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL10748478 | 0.87 | PTPN11 (0.70) | PTPN11ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL9330862 | 0.87 | PTPN11 (0.70) | PTPN11ALDH1A1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254178-A2 | Orientated polymeric material | MERCK PATENT GmbH (DE) | 1988-01-27 | — | — | EP | disclosed |