Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 2/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3168555 | 0.84 | QDPR (0.32) | QDPRPLG | |
| SCHEMBL13262405 | 0.80 | QDPR (0.35) | QDPRPLGDRD2DRD1DRD5 | |
| SCHEMBL20908872 | 0.77 | QDPR (0.38) | QDPRPLG | |
| SCHEMBL4754795 | 0.76 | — | — | |
| SCHEMBL22038 | 0.72 | — | — | |
| SCHEMBL121612 | 0.71 | — | — | |
| Lithium SCHEMBL31113350 | 0.71 | — | — | |
| SCHEMBL28135379 | 0.71 | — | — | |
| SCHEMBL9831254 | 0.71 | — | — | |
| SCHEMBL28250424 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278165-A2 | Use of 3-benzazepines in the treatment of benign prostatic hypertrophy | SMITHKLINE BEECHAM CORPORATION (US) | 1988-08-17 | — | — | EP | disclosed |