Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697444 | 0.99 | TSHR (0.36) | TSHRHPGDTHRBMEN1MAPT | |
| SCHEMBL7690555 | 0.72 | THRB (0.35) | TSHRHPGDTHRB | |
| SCHEMBL10482043 | 0.72 | THRB (0.35) | THRB | |
| SCHEMBL7685235 | 0.68 | THRB (0.32) | THRB | |
| SCHEMBL31609320 | 0.68 | TSHR (0.52) | TSHRHPGDTHRBATMTHRA | |
| SCHEMBL15572267 | 0.67 | TSHR (0.43) | TSHRHPGDTHRBATMTHRA | |
| SCHEMBL9359065 | 0.67 | TSHR (0.50) | TSHRHPGDTHRBATMTHRA | |
| SCHEMBL3385623 | 0.66 | THRB (0.33) | TSHRHPGDTHRB | |
| SCHEMBL12036658 | 0.66 | TSHR (0.48) | TSHRHPGDTHRBATMTHRA | |
| SCHEMBL3243172 | 0.66 | TSHR (0.48) | TSHRHPGDTHRBATMTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289933-A2 | Graft polymerization precurser and method manufacturing the same | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1988-11-09 | — | — | EP | disclosed |
| EP-0277608-A2 | Graft polymerization preformer and method of manufacturing the same | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1988-08-10 | — | — | EP | disclosed |