Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 11/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10699120 | 0.89 | CYP11B1 (0.56) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL79024 | 0.82 | CYP11B1 (0.67) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL10699427 | 0.78 | CYP11B1 (0.54) | CYP11B1CYP11B2CYP19A1TBXAS1 | |
| SCHEMBL10581105 | 0.78 | ALDH1A1 (0.63) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL13006744 | 0.77 | CYP11B1 (0.69) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL10579958 | 0.75 | ALDH1A1 (0.67) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL9663855 | 0.75 | CYP11B1 (0.50) | CYP11B1CYP11B2CYP19A1TBXAS1 | |
| SCHEMBL14473080 | 0.74 | CYP11B1 (0.53) | CYP11B1CYP11B2CYP19A1ALDH1A1 | |
| SCHEMBL7726168 | 0.74 | CYP11B1 (0.56) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL1024261 | 0.74 | CYP11B1 (0.84) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260744-A2 | (1H-imidazol-1-ylmethyl) substituted benzimidazole derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-03-23 | — | — | EP | disclosed |