Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 1/20 | 0.38 |
| ▸ | ATP4B | P51164 | 1/20 | 0.38 |
| ▸ | CBFB | Q13951 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6482665 | 0.87 | ATP4A (0.39) | ATP4AATP4BSLC40A1APP | |
| SCHEMBL9396516 | 0.85 | ATP4A (0.40) | ATP4AATP4BHSD17B10 | |
| SCHEMBL9395786 | 0.84 | ATP4A (0.39) | ATP4AATP4B | |
| SCHEMBL9395890 | 0.84 | ATP4A (0.39) | ATP4AATP4BHSD17B10 | |
| SCHEMBL30637598 | 0.84 | ATP4A (0.52) | ATP4AATP4BHSD17B10SLC40A1 | |
| SCHEMBL3689535 | 0.84 | ATP4A (0.52) | ATP4AATP4BHSD17B10SLC40A1 | |
| SCHEMBL10703138 | 0.83 | ATP4A (0.37) | ATP4AATP4BAPP | |
| SCHEMBL9678832 | 0.83 | ATP4A (0.39) | ATP4AATP4BSLC40A1 | |
| SCHEMBL6475466 | 0.83 | ATP4A (0.39) | ATP4AATP4BHSD17B10SLC40A1 | |
| SCHEMBL9677027 | 0.83 | KDM4E (0.39) | ATP4AATP4BHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251536-A1 | Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1988-01-07 | — | — | EP | claimed |
| EP-0251536-A1 | Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1988-01-07 | — | — | EP | disclosed |