Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 3/20 | 0.45 |
| ▸ | CCND1 | P24385 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3117662 | 0.88 | NOTUM (0.53) | NOTUMMAPK1KMT2ATSHRRAB9A | |
| SCHEMBL29384135 | 0.87 | CDK4 (0.56) | NOTUMCDK4CCND1CA12BRD4 | |
| SCHEMBL29812 | 0.87 | CDK4 (0.56) | NOTUMCDK4CCND1CA12BRD4 | |
| SCHEMBL7505128 | 0.87 | MAPK1 (0.54) | NOTUMMAPK1KMT2ATSHRRAB9A | |
| Formaldehyde SCHEMBL27911684 | 0.85 | CDK4 (0.50) | NOTUMMAPK1KMT2ATSHRRAB9A | |
| Bromide SCHEMBL6480413 | 0.85 | CDK4 (0.54) | NOTUMCDK4CCND1CA12BRD4 | |
| Bromide SCHEMBL31591097 | 0.85 | CDK4 (0.54) | NOTUMCDK4CCND1CA12BRD4 | |
| Hydrochloric Acid SCHEMBL30610362 | 0.85 | CDK4 (0.54) | NOTUMCDK4CCND1CA12BRD4 | |
| Hydrochloric Acid SCHEMBL1356443 | 0.85 | CDK4 (0.54) | NOTUMCDK4CCND1CA12BRD4 | |
| SCHEMBL3867839 | 0.84 | NOTUM (0.48) | NOTUMMAPK1KMT2ATSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120004784-A | New method for preparing aromatic aldehyde compound | 广东海洋大学 | 2025-05-16 | — | — | CN | disclosed |
| CN-115286625-B | Glutaminase allosteric site covalent inhibitor and preparation method and application thereof | 浙江工业大学 | 2025-03-25 | — | — | CN | disclosed |
| CN-115286625-A | Glutaminase allosteric site covalent inhibitor and preparation method and application thereof | 浙江工业大学 | 2022-11-04 | — | — | CN | disclosed |
| EP-0268429-A2 | Photoinitiator composition | MORTON INTERNATIONAL, INC. (US) | 1988-05-25 | — | — | EP | disclosed |