Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | TGM1 | P22735 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10700264 | 0.91 | ALDH1A1 (0.46) | KDM4EALDH1A1LMNAGAATSHR | |
| SCHEMBL10699756 | 0.88 | ALDH1A1 (0.45) | KDM4EALDH1A1LMNAGAATSHR | |
| SCHEMBL10698416 | 0.87 | MEN1 (0.37) | KDM4EALDH1A1LMNAGAANPSR1 | |
| SCHEMBL10695097 | 0.87 | PARP1 (0.40) | KDM4EALDH1A1LMNAGAATSHR | |
| SCHEMBL10700981 | 0.83 | MEN1 (0.37) | KDM4EALDH1A1LMNAGAANPSR1 | |
| SCHEMBL10698855 | 0.80 | CYP11B1 (0.49) | MAPTMEN1KMT2ADHFR | |
| SCHEMBL10697536 | 0.80 | MEN1 (0.35) | KDM4EALDH1A1HSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL10699877 | 0.79 | MEN1 (0.41) | KDM4EALDH1A1LMNAGAAHSD17B10 | |
| SCHEMBL10699273 | 0.78 | DHODH (0.39) | KDM4EALDH1A1GAAHSD17B10NPC1 | |
| SCHEMBL10699753 | 0.78 | KDM4E (0.41) | KDM4EALDH1A1LMNAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |