Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627465 | 0.93 | HTT (0.69) | HTTTNFSF11TSHRKDM4EHSD17B10 | |
| SCHEMBL9627466 | 0.88 | HTT (0.61) | HTTTNFSF11TSHRKDM4EHSD17B10 | |
| SCHEMBL9628345 | 0.86 | HTT (0.56) | HTTTNFSF11TSHRKDM4EHSD17B10 | |
| SCHEMBL9627451 | 0.86 | HTT (0.56) | HTTTNFSF11TSHRKDM4EHSD17B10 | |
| SCHEMBL9660313 | 0.85 | KDM4E (0.47) | HTTTSHRKDM4EHSD17B10TUBB4A | |
| SCHEMBL7918996 | 0.84 | HTT (0.75) | HTTTNFSF11TSHRKDM4EHSD17B10 | |
| SCHEMBL30226958 | 0.84 | HTT (0.54) | HTTTNFSF11TSHRKDM4EHSD17B10 | |
| SCHEMBL9628323 | 0.84 | HTT (0.54) | HTTTNFSF11TSHRKDM4EHSD17B10 | |
| SCHEMBL23535302 | 0.84 | HTT (0.60) | HTTTNFSF11TSHRKDM4EHSD17B10 | |
| SCHEMBL9629380 | 0.83 | HTT (0.55) | HTTTNFSF11TSHRKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282056-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | claimed |