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Propionic Acid

Propionic Acid

SCHEMBL10698835

CCC(=O)O.CCCCCCCCCCOc1ccc(C(=O)c2cccc(C(=O)O)c2)cc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TP53 P04637 1/20 0.68
▸ TSHR P16473 1/20 0.68
▸ PLA2G4B P0C869 7/20 0.66
▸ RARB P10826 3/20 0.63
▸ LTB4R Q15722 1/20 0.63
▸ NR1H4 Q96RI1 2/20 0.61
▸ PLA2G4A P47712 1/20 0.60
▸ PTPN11 Q06124 1/20 0.57
▸ PPARA Q07869 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL10695213 0.94 TP53 (0.69) TP53TSHRPLA2G4BRARBLTB4R
Acetic Acid SCHEMBL10697082 0.94 TP53 (0.69) TP53TSHRPLA2G4BRARBLTB4R
Butyric Acid SCHEMBL10698932 0.93 LTB4R (0.67) TP53TSHRPLA2G4BRARBLTB4R
Propionic Acid SCHEMBL9445378 0.88 PLA2G4B (0.56) TP53TSHRPLA2G4BRARBLTB4R
SCHEMBL18774788 0.86 TP53 (0.73) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL534753 0.86 TP53 (0.73) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL534947 0.86 TP53 (0.73) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL6648277 0.86 TP53 (0.73) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL11001285 0.86 TP53 (0.73) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL7921632 0.86 TP53 (0.73) TP53TSHRPLA2G4BRARBPLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0276064-A1 Anti-inflammatory agents ELI LILLY AND COMPANY (US) 1988-07-27 — — EP disclosed