Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.52 |
| ▸ | RARB | P10826 | 3/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698939 | 0.93 | TP53 (0.51) | TP53TSHRCYP19A1PLA2G4BRARB | |
| SCHEMBL10695219 | 0.90 | TP53 (0.53) | TP53TSHRCYP19A1PLA2G4BRARB | |
| SCHEMBL10697087 | 0.90 | TP53 (0.53) | TP53TSHRCYP19A1PLA2G4BRARB | |
| SCHEMBL10426194 | 0.86 | SMPD1 (0.65) | TSHRPLA2G4BNR1H4SMPD1THRA | |
| SCHEMBL10700254 | 0.85 | PLA2G4B (0.58) | TP53TSHRPLA2G4BNR1H4LMNA | |
| Propionic Acid SCHEMBL10698835 | 0.85 | TP53 (0.68) | TP53TSHRPLA2G4BRARBNR1H4 | |
| Acetic Acid SCHEMBL10695213 | 0.84 | TP53 (0.69) | TP53TSHRPLA2G4BRARBNR1H4 | |
| Acetic Acid SCHEMBL10697082 | 0.84 | TP53 (0.69) | TP53TSHRPLA2G4BRARBNR1H4 | |
| SCHEMBL11001285 | 0.81 | TP53 (0.73) | TP53TSHRPLA2G4BRARBLMNA | |
| SCHEMBL18774788 | 0.81 | TP53 (0.73) | TP53TSHRPLA2G4BRARBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276064-A1 | Anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1988-07-27 | — | — | EP | disclosed |