Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 8/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 8/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 8/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28672094 | 0.82 | SLC1A3 (0.52) | SLC1A3SLC1A2SLC1A1SLC7A5ACHE | |
| SCHEMBL9235975 | 0.79 | SLC1A3 (0.41) | SLC1A3SLC1A2SLC1A1SLC7A5ACHE | |
| SCHEMBL10373135 | 0.76 | SLC1A3 (0.34) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7636697 | 0.74 | SLC1A3 (0.33) | SLC1A3SLC1A2SLC1A1SLC7A5 | |
| SCHEMBL2231192 | 0.74 | TDP1 (0.37) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7279279 | 0.73 | CYP2C19 (0.43) | SLC1A3SLC1A2SLC1A1 | |
| Isoleucine SCHEMBL9117832 | 0.71 | SLC1A3 (0.45) | SLC1A3SLC1A2SLC1A1SLC7A5 | |
| SCHEMBL755924 | 0.70 | SLC7A5 (0.50) | SLC1A3SLC1A2SLC1A1SLC7A5USP2 | |
| SCHEMBL2424284 | 0.70 | — | — | |
| SCHEMBL1168875 | 0.70 | SLC7A5 (0.50) | SLC1A3SLC1A2SLC1A1SLC7A5USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260778-A1 | Enzymatic process for B-Lactams | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) | 1988-03-23 | — | — | EP | disclosed |