Isoleucine

Isoleucine

SCHEMBL9117832

CCC(C)C(N)C(=O)O.COC(C)C(N)C(=O)O

nearest known ligand 0.45

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.45
SLC1A2 P43004 1/20 0.45
SLC1A1 P43005 1/20 0.45
SLC7A5 Q01650 1/20 0.41
DPP4 P27487 12/20 0.40
DPP8 Q6V1X1 8/20 0.40
DPP9 Q86TI2 7/20 0.40
DPP7 Q9UHL4 7/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoleucine SCHEMBL9117841 1.00 SLC1A3 (0.45) SLC1A3SLC1A2SLC1A1SLC7A5DPP4
Isoleucine SCHEMBL1255583 0.85 SLC7A5 (0.55) SLC1A3SLC1A2SLC1A1SLC7A5DPP4
Isoleucine SCHEMBL20340795 0.85
SCHEMBL6092471 0.85
Isoleucine SCHEMBL8186739 0.85 SLC7A5 (0.55) SLC1A3SLC1A2SLC1A1SLC7A5DPP4
Isoleucine SCHEMBL8045737 0.85 SLC7A5 (0.55) SLC1A3SLC1A2SLC1A1SLC7A5DPP4
SCHEMBL9654638 0.85
Isoleucine SCHEMBL8043620 0.85 SLC7A5 (0.55) SLC1A3SLC1A2SLC1A1SLC7A5DPP4
SCHEMBL9654503 0.85
Isoleucine SCHEMBL1255582 0.85 SLC7A5 (0.55) SLC1A3SLC1A2SLC1A1SLC7A5DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0288087-B1 Method for producing protein containing nonprotein amino acids WAKUNAGA SEIYAKU KK (JP) 1995-02-22 EP disclosed
US-4879223-A Method for producing protein containing nonprotein amino acids WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1989-11-07 US disclosed
EP-0288087-A2 Method for producing protein containing nonprotein amino acids WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1988-10-26 EP disclosed