Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.58 |
| ▸ | OSBP | P22059 | 4/20 | 0.56 |
| ▸ | RORC | P51449 | 3/20 | 0.56 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | OSBP2 | Q969R2 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.49 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | CRYAB | P02511 | 1/20 | 0.47 |
| ▸ | HMGCR | P04035 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11324759 | 0.89 | POLA1 (0.56) | POLA1OSBPRORCCYP46A1USP2 | |
| SCHEMBL7876330 | 0.88 | POLA1 (0.59) | POLA1OSBPRORCCYP46A1USP2 | |
| SCHEMBL11324755 | 0.84 | OSBP (0.56) | POLA1OSBPRORCCYP46A1USP2 | |
| SCHEMBL7872684 | 0.83 | POLA1 (0.55) | POLA1OSBPRORCCYP46A1USP2 | |
| SCHEMBL7876329 | 0.82 | OSBP (0.59) | POLA1OSBPRORCCYP46A1USP2 | |
| SCHEMBL8638259 | 0.82 | POLA1 (0.55) | POLA1OSBPRORCCYP46A1USP2 | |
| SCHEMBL9845558 | 0.82 | POLA1 (0.63) | POLA1OSBPRORCCYP46A1USP2 | |
| SCHEMBL9122037 | 0.82 | POLA1 (0.57) | POLA1OSBPRORCCYP46A1USP2 | |
| SCHEMBL9446923 | 0.82 | POLA1 (0.59) | POLA1OSBPRORCCYP46A1USP2 | |
| SCHEMBL2863613 | 0.81 | OSBP (0.63) | POLA1OSBPRORCCYP46A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3974317-A | CHOLESTERIC LIQUID CRYSTAL SYSTEM | ASHLEY-BUTLER, INC. (US) | 1976-08-10 | — | — | US | claimed |
| EP-0260923-A2 | Temperature sensing composition | MEDICAL INDICATORS (a limited partnership under US law) (US) | 1988-03-23 | — | — | EP | disclosed |
| US-3974317-A | CHOLESTERIC LIQUID CRYSTAL SYSTEM | ASHLEY-BUTLER, INC. (US) | 1976-08-10 | — | — | US | disclosed |