SCHEMBL8638259

SCHEMBL8638259

C=CC(=O)OCCCCCCOc1ccc(C(=O)O)c([C@H]2CC[C@@]3(C)C(=CC[C@H]4[C@@H]5CC[C@H]([C@H](C)CCCC(C)C)[C@@]5(C)CC[C@@H]43)C2)c1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLA1 P09884 1/20 0.55
OSBP P22059 3/20 0.53
CYP46A1 Q9Y6A2 2/20 0.53
USP2 O75604 2/20 0.53
RORC P51449 2/20 0.53
LMNA P02545 1/20 0.53
ABCB1 P08183 1/20 0.53
OSBP2 Q969R2 1/20 0.53
PLA2G2A P14555 1/20 0.48
GBA1 P04062 2/20 0.47
UGCG Q16739 2/20 0.47
GBA2 Q9HCG7 2/20 0.47
NR1H3 Q13133 3/20 0.47
EPHA2 P29317 2/20 0.47
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
FNTA P49354 1/20 0.45
FNTB P49356 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7872684 0.92 POLA1 (0.55) POLA1OSBPCYP46A1USP2RORC
SCHEMBL9122037 0.91 POLA1 (0.57) POLA1OSBPCYP46A1USP2RORC
SCHEMBL9446923 0.88 POLA1 (0.59) POLA1OSBPCYP46A1USP2RORC
SCHEMBL7561230 0.88 POLA1 (0.54) POLA1OSBPCYP46A1USP2RORC
SCHEMBL6931519 0.86 POLA1 (0.57) POLA1OSBPCYP46A1USP2RORC
SCHEMBL9446912 0.84 POLA1 (0.64) POLA1OSBPCYP46A1USP2RORC
SCHEMBL8436531 0.84 POLA1 (0.54) POLA1OSBPCYP46A1USP2RORC
SCHEMBL18470121 0.84 POLA1 (0.59) POLA1OSBPCYP46A1USP2RORC
SCHEMBL7655422 0.84 POLA1 (0.59) POLA1OSBPCYP46A1USP2RORC
SCHEMBL7655418 0.84 POLA1 (0.59) POLA1OSBPCYP46A1USP2RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0869112-A1 Compounds, method for preparing them and preparation of liquid crystal polymers by using these compounds Daimler-Benz Aktiengesellschaft (DE) 1998-10-07 EP disclosed
EP-0760836-B1 EFFECT LACQUER AND LACQUERING, IN PARTICULAR FOR CAR BODIES, BY MEANS OF LIQUID CRYSTAL INTERFERENCE PIGMENTS DAIMLER BENZ AG (DE) 1998-07-29 EP disclosed
EP-0837054-A2 Compounds and their use as well as a process for the preparation of polymeric liquid crystals therefrom Daimler-Benz Aktiengesellschaft (DE) 1998-04-22 EP disclosed
EP-0760836-A1 EFFECT LACQUER AND LACQUERING, IN PARTICULAR FOR CAR BODIES, BY MEANS OF LIQUID CRYSTAL INTERFERENCE PIGMENTS DAIMLER-BENZ AKTIENGESELLSCHAFT (DE) 1997-03-12 EP disclosed
WO-1995032247-A1 EFFECT LACQUER AND LACQUERING, IN PARTICULAR FOR CAR BODIES, BY MEANS OF LIQUID CRYSTAL INTERFERENCE PIGMENTS DAIMLER-BENZ AKTIENGESELLSCHAFT (DE) 1995-11-30 WO disclosed