Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10702810 | 0.94 | LMNA (0.34) | LMNAKMT2AMEN1CCKBRADAMTS5 | |
| SCHEMBL10700881 | 0.88 | LMNA (0.36) | LMNAKMT2AMEN1CCKBRADAMTS5 | |
| SCHEMBL10699826 | 0.88 | LMNA (0.35) | LMNAKMT2AMEN1CCKBRSMN1; SMN2 | |
| SCHEMBL10699846 | 0.87 | LMNA (0.33) | LMNAKMT2AMEN1CCKBRSMN1; SMN2 | |
| SCHEMBL10702632 | 0.87 | — | — | |
| SCHEMBL10700830 | 0.85 | LMNA (0.35) | LMNAKMT2AMEN1CCKBR | |
| SCHEMBL10699319 | 0.83 | LMNA (0.35) | LMNAKMT2AMEN1CCKBRSMN1; SMN2 | |
| SCHEMBL10701030 | 0.83 | LMNA (0.34) | LMNAKMT2AMEN1CCKBRSMN1; SMN2 | |
| SCHEMBL10702663 | 0.81 | LMNA (0.36) | LMNAKMT2AMEN1CCKBRADAMTS5 | |
| SCHEMBL10699951 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293532-A1 | 6- or 7-beta-[2-[4-(substituted)-2,3-dioxopiperazin-1-yl) carbonylamino]-(substituted)acetamido]-penicillin and cephalosporin derivatives | BEECHAM GROUP PLC (GB) | 1988-12-07 | — | — | EP | disclosed |