Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 13/20 | 0.34 |
| ▸ | CA2 | P00918 | 13/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10700846 | 0.88 | MEN1 (0.39) | MEN1KMT2ACCKBRLMNACA1 | |
| Benzene SCHEMBL10702058 | 0.87 | LMNA (0.38) | MEN1KMT2ACCKBRLMNACA1 | |
| SCHEMBL10700810 | 0.87 | MEN1 (0.38) | MEN1KMT2ACCKBRLMNACA1 | |
| SCHEMBL10493032 | 0.84 | MAPT (0.39) | MEN1KMT2ACCKBRLMNATDP1 | |
| SCHEMBL11157011 | 0.84 | MAPT (0.39) | MEN1KMT2ACCKBRLMNATDP1 | |
| SCHEMBL10701775 | 0.84 | MEN1 (0.39) | MEN1KMT2ACCKBRLMNACA1 | |
| SCHEMBL10701516 | 0.83 | MEN1 (0.38) | MEN1KMT2ACCKBRLMNACA1 | |
| SCHEMBL10701799 | 0.83 | MAPT (0.37) | MEN1KMT2ACCKBRLMNACA1 | |
| SCHEMBL10701237 | 0.81 | LMNA (0.40) | MEN1KMT2ACCKBRLMNACA1 | |
| SCHEMBL10493303 | 0.81 | MAPT (0.45) | MEN1KMT2ACCKBRLMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293532-A1 | 6- or 7-beta-[2-[4-(substituted)-2,3-dioxopiperazin-1-yl) carbonylamino]-(substituted)acetamido]-penicillin and cephalosporin derivatives | BEECHAM GROUP PLC (GB) | 1988-12-07 | — | — | EP | claimed |
| EP-0293532-A1 | 6- or 7-beta-[2-[4-(substituted)-2,3-dioxopiperazin-1-yl) carbonylamino]-(substituted)acetamido]-penicillin and cephalosporin derivatives | BEECHAM GROUP PLC (GB) | 1988-12-07 | — | — | EP | disclosed |