Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ATP4A | P20648 | 1/20 | 0.30 |
| ▸ | ATP4B | P51164 | 1/20 | 0.30 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
| ▸ | TUBB | P07437 | 1/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.30 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.30 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.30 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.30 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3692343 | 0.87 | NQO2 (0.35) | P2RX7ATP4AATP4B | |
| SCHEMBL10700093 | 0.85 | GAA (0.33) | IGF1RP2RX7DHFRGAAKDM4E | |
| SCHEMBL10701306 | 0.84 | ATP4A (0.33) | P2RX7ATP4AATP4B | |
| SCHEMBL10701062 | 0.80 | SMN1; SMN2 (0.40) | P2RX7KDM4EALDH1A1HSD17B10TP53 | |
| SCHEMBL10701843 | 0.79 | PRMT5 (0.33) | P2RX7GAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL10701999 | 0.79 | OGT (0.34) | KDM4EHSD17B10TP53MAPTATP4A | |
| SCHEMBL9695446 | 0.78 | PRMT5 (0.41) | P2RX7ALDH1A1HSD17B10TP53ATP4A | |
| SCHEMBL9678434 | 0.78 | PDE10A (0.39) | P2RX7KDM4EALDH1A1ATP4AATP4B | |
| SCHEMBL10699893 | 0.78 | SMN1; SMN2 (0.45) | ALDH1A1MAPT | |
| SCHEMBL9576670 | 0.77 | NQO2 (0.34) | P2RX7ATP4AATP4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251536-A1 | Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1988-01-07 | — | — | EP | claimed |
| EP-0251536-A1 | Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1988-01-07 | — | — | EP | disclosed |