⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10702968 | 0.94 | LMNA (0.30) | — | |
| SCHEMBL10700366 | 0.90 | MEN1 (0.31) | — | |
| SCHEMBL10700221 | 0.89 | MEN1 (0.37) | — | |
| SCHEMBL10699951 | 0.85 | — | — | |
| SCHEMBL10700293 | 0.84 | LMNA (0.32) | — | |
| SCHEMBL10701748 | 0.81 | MEN1 (0.37) | — | |
| SCHEMBL10701799 | 0.79 | MAPT (0.37) | — | |
| SCHEMBL10834483 | 0.79 | MAPT (0.36) | — | |
| SCHEMBL10493034 | 0.79 | MAPT (0.36) | — | |
| SCHEMBL10700846 | 0.78 | MEN1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293532-A1 | 6- or 7-beta-[2-[4-(substituted)-2,3-dioxopiperazin-1-yl) carbonylamino]-(substituted)acetamido]-penicillin and cephalosporin derivatives | BEECHAM GROUP PLC (GB) | 1988-12-07 | — | — | EP | claimed |