Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 10/20 | 0.41 |
| ▸ | DRD2 | P14416 | 5/20 | 0.41 |
| ▸ | DRD5 | P21918 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | THPO | P40225 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10700513 | 0.84 | CYP3A4 (0.47) | DRD1DRD2DRD5SMN1; SMN2KDM4E | |
| SCHEMBL11169289 | 0.75 | CYP3A4 (0.38) | DRD1DRD5SMN1; SMN2KDM4EMAPT | |
| Fumaric Acid SCHEMBL10702753 | 0.74 | SMN1; SMN2 (0.51) | DRD1DRD2DRD5MAPK1SMN1; SMN2 | |
| Fumaric Acid SCHEMBL10702746 | 0.74 | SMN1; SMN2 (0.51) | DRD1DRD2DRD5MAPK1SMN1; SMN2 | |
| SCHEMBL11169440 | 0.74 | KDM4E (0.32) | DRD1DRD2DRD5SMN1; SMN2KDM4E | |
| SCHEMBL10701951 | 0.70 | DRD1 (0.49) | DRD1DRD2DRD5SMN1; SMN2 | |
| SCHEMBL5462704 | 0.66 | ESR1 (0.47) | DRD1DRD2DRD5KDM4ESIGMAR1 | |
| SCHEMBL10110765 | 0.64 | KDM4C (0.49) | ALOX15 | |
| SCHEMBL7616589 | 0.63 | DRD1 (0.68) | DRD1DRD2DRD5HSD17B10THPO | |
| SCHEMBL11566588 | 0.63 | DRD1 (0.68) | DRD1DRD2DRD5HSD17B10THPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285287-A2 | 3-Benzazepine compounds for use in treating gastrointestinal motility disorders | SMITHKLINE BEECHAM CORPORATION (US) | 1988-10-05 | — | — | EP | disclosed |