SCHEMBL10703085

SCHEMBL10703085

CCCC(=Cc1ccccc1)C(=O)OCl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
AKR1C3 P42330 1/20 0.46
CYP3A4 P08684 1/20 0.45
CYP2C9 P11712 1/20 0.45
LMNA P02545 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.42
NR1I2 O75469 1/20 0.41
NR1H4 Q96RI1 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MTNR1A P48039 2/20 0.40
MTNR1B P49286 2/20 0.40
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10703081 1.00 RECQL (0.51) RECQLMEN1KMT2AAKR1C3CYP3A4
SCHEMBL11818250 0.87 RECQL (0.51) RECQLMEN1KMT2AAKR1C3CYP3A4
SCHEMBL11818255 0.87 RECQL (0.51) RECQLMEN1KMT2AAKR1C3CYP3A4
SCHEMBL3146136 0.84 RECQL (0.66) RECQLMEN1KMT2AAKR1C3CYP3A4
SCHEMBL3151228 0.84 RECQL (0.66) RECQLMEN1KMT2AAKR1C3CYP3A4
SCHEMBL3146140 0.84 RECQL (0.66) RECQLMEN1KMT2AAKR1C3CYP3A4
SCHEMBL8858244 0.82 CYP3A4 (0.59) RECQLMEN1KMT2AAKR1C3CYP3A4
SCHEMBL3256825 0.82 CYP3A4 (0.59) RECQLMEN1KMT2AAKR1C3CYP3A4
SCHEMBL28807455 0.81 MEN1 (0.46) RECQLMEN1KMT2AAKR1C3CYP3A4
SCHEMBL7917274 0.79 RECQL (0.50) RECQLMEN1KMT2AAKR1C3CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0156726-B1 PROCESS FOR THE PREPARATION OF A SMECTIC C-CHIRAL FERROELECTRIC LIQUID CRYSTAL, LIQUID CRYSTAL AND DISPLAY DEVICE USING THE SAME. THOMSON-CSF (FR) 1988-01-13 EP disclosed
EP-0239444-A1 Ferroelectric liquid crystal, process for its manufacture and its use in a liquid-crystal mixture THOMSON-CSF (FR) 1987-09-30 EP disclosed