Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 3/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | PTGFR | P43088 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10704350 | 0.90 | PTGIR (0.41) | PTGIRPTGER4PTGER2NR1I2ESR1 | |
| SCHEMBL10353583 | 0.90 | PTGIR (0.41) | PTGIRPTGER4PTGER2NR1I2ESR1 | |
| SCHEMBL11387487 | 0.87 | PTGIR (0.34) | PTGIRPTGER4PTGER2PGRHPGD | |
| SCHEMBL10702023 | 0.85 | PDE4D (0.35) | PTGIRPTGER4HPGDTSHRTBXA2R | |
| SCHEMBL10701433 | 0.85 | PDE4D (0.35) | PTGIRPTGER4HPGDTSHRTBXA2R | |
| SCHEMBL11389584 | 0.85 | PTGER3 (0.34) | PTGIRPTGER4PTGER2NR1I2ESR1 | |
| SCHEMBL11380894 | 0.85 | PTGIR (0.34) | PTGIRPTGER4PTGER2NR1I2ESR1 | |
| SCHEMBL10353179 | 0.85 | PTGIR (0.33) | PTGIR | |
| SCHEMBL10353925 | 0.84 | PTGIR (0.32) | PTGIR | |
| SCHEMBL11393376 | 0.84 | ALDH1A1 (0.32) | PTGIRPTGER4PTGER2PGRPTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0156611-B1 | INTERMEDIATES FOR THE PREPARATION OF PROSTAGLANDIN ANALOGUES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |
| US-4622410-A | CHEMICAL INTERMEDIATES FOR 6-KETO-PROSTAGLANDINS | ONO PHARMACEUTICAL CO. LTD. (JP) | 1986-11-11 | — | — | US | disclosed |
| EP-0156611-A2 | Intermediates for the preparation of prostaglandin analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1985-10-02 | — | — | EP | disclosed |