Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 6/20 | 0.46 |
| ▸ | YAP1 | P46937 | 3/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1013961 | 1.00 | STS (0.46) | STSYAP1TGFBR1ADAM17MCL1 | |
| SCHEMBL1013962 | 1.00 | STS (0.46) | STSYAP1TGFBR1ADAM17MCL1 | |
| SCHEMBL14278078 | 0.87 | MCL1 (0.37) | STSADAM17MCL1 | |
| SCHEMBL14278217 | 0.87 | MCL1 (0.37) | STSADAM17MCL1 | |
| SCHEMBL1013790 | 0.85 | TACR1 (0.40) | STSADAM17MCL1 | |
| SCHEMBL1013789 | 0.85 | TACR1 (0.40) | STSADAM17MCL1 | |
| SCHEMBL14278109 | 0.85 | TACR1 (0.40) | STSADAM17MCL1 | |
| SCHEMBL4791746 | 0.85 | BCL2 (0.44) | ADAM17MCL1 | |
| SCHEMBL1014380 | 0.85 | BCL2 (0.44) | ADAM17MCL1 | |
| SCHEMBL14278201 | 0.83 | ADAM17 (0.39) | ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272858-A2 | HCV inhibitors comprising beta amino acids and their uses | Novartis AG (CH) | 2011-01-12 | — | — | EP | disclosed |