Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10703856 | 0.87 | NPC1 (0.43) | NPC1RAB9AMEN1KMT2ACNR1 | |
| SCHEMBL10711569 | 0.85 | MEN1 (0.43) | NPC1RAB9AMEN1KMT2AITGB1 | |
| SCHEMBL10706436 | 0.85 | HDAC6 (0.46) | NPC1RAB9AMEN1KMT2ACNR1 | |
| SCHEMBL10703862 | 0.84 | NPC1 (0.45) | NPC1RAB9AMEN1KMT2ACNR1 | |
| SCHEMBL10703872 | 0.84 | HDAC6 (0.43) | NPC1RAB9AMEN1KMT2ACNR1 | |
| SCHEMBL10711319 | 0.84 | NPC1 (0.43) | NPC1RAB9AMEN1KMT2AITGB1 | |
| SCHEMBL10714679 | 0.83 | HDAC6 (0.43) | NPC1RAB9AMEN1KMT2ACNR1 | |
| SCHEMBL10712873 | 0.83 | RAB9A (0.47) | NPC1RAB9AMEN1KMT2AITGB1 | |
| SCHEMBL10708895 | 0.82 | GCGR (0.52) | NPC1RAB9AMEN1KMT2APKM | |
| Diflubenzuron SCHEMBL42416 | 0.81 | RAB9A (0.59) | NPC1RAB9AMEN1KMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116729-B1 | BENZOYLUREA COMPOUNDS AND PESTICIDAL COMPOSITIONS COMPRISINGSAME | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-10-12 | — | — | EP | disclosed |
| US-4710516-A | Insecticidal and acaricidal composition comprising a benzoylurea compound | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1987-12-01 | — | — | US | disclosed |
| US-4665235-A | INSECTICIDES, MITICIDES, ANTITUMOR AGENTS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1987-05-12 | — | — | US | disclosed |
| EP-0116729-A2 | Benzoylurea compounds and pesticidal compositions comprisingsame | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1984-08-29 | — | — | EP | disclosed |