Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 8/20 | 0.45 |
| ▸ | CTSB | P07858 | 6/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530387 | 0.85 | PRSS1 (0.60) | PRSS1PRSS2PRSS3TPSAB1ITGB3 | |
| SCHEMBL29087638 | 0.84 | PRSS1 (0.54) | PRSS1PRSS2PRSS3TPSAB1ITGB3 | |
| SCHEMBL23044896 | 0.82 | ITGB3 (0.58) | PRSS1PRSS2PRSS3TPSAB1ITGB3 | |
| SCHEMBL15519969 | 0.82 | ITGB3 (0.58) | PRSS1PRSS2PRSS3TPSAB1ITGB3 | |
| SCHEMBL10723335 | 0.82 | PRSS1 (0.61) | PRSS1PRSS2PRSS3TPSAB1ITGB3 | |
| SCHEMBL1841203 | 0.82 | PRSS1 (0.61) | PRSS1PRSS2PRSS3TPSAB1ITGB3 | |
| SCHEMBL1841202 | 0.82 | PRSS1 (0.61) | PRSS1PRSS2PRSS3TPSAB1ITGB3 | |
| Hydrochloric Acid SCHEMBL8533423 | 0.81 | PRSS1 (0.60) | PRSS1PRSS2PRSS3TPSAB1ITGB3 | |
| SCHEMBL2778594 | 0.81 | ITGB3 (0.53) | PRSS1PRSS2PRSS3TPSAB1ITGB3 | |
| SCHEMBL8447232 | 0.80 | SIRT2 (0.59) | PRSS1PRSS2PRSS3TPSAB1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295316-A2 | Antitumor amino acid and peptide derivatives of 1,4-bis[ (aminoalkyl and hydroxyaminoalkyl)- amino]-5,8 dihydroxyanthraquinones | AMERICAN CYANAMID COMPANY (US) | 1988-12-21 | — | — | EP | disclosed |