SCHEMBL10705357

SCHEMBL10705357

O=C(/C=C/c1ccc(OCC2CO2)cc1)c1ccc(OCC2CO2)cc1

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAOB P27338 9/20 0.56
ABCG2 Q9UNQ0 4/20 0.56
F3 P13726 1/20 0.54
MAPT P10636 2/20 0.53
MAOA P21397 1/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
KMT2A Q03164 1/20 0.53
KDM4E B2RXH2 1/20 0.52
LMNA P02545 1/20 0.52
POLB P06746 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
HRH3 Q9Y5N1 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10703802 1.00 MAOB (0.56) MAOBABCG2F3MAPTMAOA
SCHEMBL10705363 1.00 MAOB (0.56) MAOBABCG2F3MAPTMAOA
SCHEMBL10704289 1.00 MAOB (0.56) MAOBABCG2F3MAPTMAOA
SCHEMBL3440624 0.94 MAOB (0.67) MAOBF3MAPTMAOANPC1
SCHEMBL3440623 0.94 MAOB (0.67) MAOBF3MAPTMAOANPC1
SCHEMBL10353006 0.87 ALDH1A1 (0.53) F3MAPTNPC1RAB9AKMT2A
SCHEMBL9513254 0.87 ALDH1A1 (0.53) F3MAPTNPC1RAB9AKMT2A
SCHEMBL9513259 0.87 ALDH1A1 (0.53) F3MAPTNPC1RAB9AKMT2A
SCHEMBL3440517 0.86 MAPT (0.70) ABCG2MAPTNPC1RAB9AKMT2A
SCHEMBL3440675 0.86 MAPT (0.61) MAOBABCG2MAPTMAOANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0115471-B1 IMAGE-FORMING PROCESS CIBA-GEIGY AG (CH) 1988-02-10 EP claimed
US-4546067-A Image production utilizing multifunctional light sensitive compounds CIBA GEIGY CORPORATION (US) 1985-10-08 US claimed
US-4546067-A Image production utilizing multifunctional light sensitive compounds CIBA GEIGY CORPORATION (US) 1985-10-08 US disclosed