Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10681013 | 0.98 | NAAA (0.54) | NAAAMAPTSMN1; SMN2CYP1A2POLB | |
| SCHEMBL10681016 | 0.98 | NAAA (0.54) | NAAAMAPTSMN1; SMN2CYP1A2POLB | |
| SCHEMBL10705977 | 0.95 | NAAA (0.58) | NAAAMAPTSMN1; SMN2CYP1A2LMNA | |
| SCHEMBL10706724 | 0.95 | NAAA (0.62) | NAAAMAPTSMN1; SMN2LMNAPRKCA | |
| SCHEMBL10706485 | 0.94 | NAAA (0.65) | NAAAMAPTSMN1; SMN2LMNAPRKCA | |
| SCHEMBL10704209 | 0.94 | NAAA (0.65) | NAAAMAPTSMN1; SMN2LMNAPRKCA | |
| SCHEMBL10707955 | 0.94 | NAAA (0.60) | NAAAMAPTSMN1; SMN2CYP1A2LMNA | |
| SCHEMBL10676984 | 0.94 | NAAA (0.56) | NAAAMAPTSMN1; SMN2CYP1A2LMNA | |
| SCHEMBL10676990 | 0.94 | NAAA (0.56) | NAAAMAPTSMN1; SMN2CYP1A2LMNA | |
| SCHEMBL10705768 | 0.94 | NAAA (0.60) | NAAAMAPTSMN1; SMN2CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168701-B1 | TERCYCLOHEXYLES | MERCK PATENT GmbH (DE) | 1988-11-02 | — | — | EP | disclosed |