Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 13/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627630 | 0.84 | ELANE (0.47) | ELANEHTTALDH1A1ESR1LMNA | |
| SCHEMBL10710043 | 0.83 | ELANE (0.41) | ELANEHTTALDH1A1LMNACYP3A4 | |
| SCHEMBL9627634 | 0.81 | HTT (0.63) | HTTALDH1A1ACHEIRAK4ESR1 | |
| SCHEMBL10704405 | 0.81 | ELANE (0.45) | ELANEHTTALDH1A1ESR1LMNA | |
| SCHEMBL9627373 | 0.81 | ELANE (0.44) | ELANEHTTALDH1A1LMNACYP3A4 | |
| SCHEMBL10703543 | 0.80 | HTT (0.43) | ELANEHTTALDH1A1ACHEIRAK4 | |
| SCHEMBL9628421 | 0.80 | ELANE (0.45) | ELANEHTTALDH1A1ESR1 | |
| SCHEMBL10705564 | 0.79 | HTT (0.42) | ELANEHTTALDH1A1ACHEIRAK4 | |
| SCHEMBL10704565 | 0.78 | CNR1 (0.42) | ELANEHTTALDH1A1LMNACYP3A4 | |
| SCHEMBL9627462 | 0.78 | ELANE (0.47) | ELANEHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |