Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627599 | 0.87 | HTT (0.44) | HTTALDH1A1ALOX15ELANEKLKB1 | |
| SCHEMBL9627634 | 0.84 | HTT (0.63) | HTTALDH1A1ACHEIRAK4KMT2A | |
| SCHEMBL9628373 | 0.83 | SLC2A1 (0.43) | HTTALDH1A1ALOX15KLKB1KMT2A | |
| SCHEMBL10707130 | 0.83 | ELANE (0.42) | HTTALOX15ELANEKLKB1MEN1 | |
| SCHEMBL30003194 | 0.82 | HTT (0.65) | HTTALDH1A1ALOX15ELANEKLKB1 | |
| SCHEMBL10705564 | 0.81 | HTT (0.42) | HTTALDH1A1ACHEIRAK4ALOX15 | |
| SCHEMBL10705634 | 0.81 | CNR1 (0.42) | HTTALDH1A1ALOX15ELANEKLKB1 | |
| SCHEMBL30003139 | 0.81 | ALOX15 (0.47) | HTTALOX15ELANEKLKB1MEN1 | |
| SCHEMBL10705899 | 0.80 | ELANE (0.44) | HTTALDH1A1ACHEIRAK4ELANE | |
| SCHEMBL20398569 | 0.79 | ELANE (0.50) | HTTALDH1A1ALOX15ELANEKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |